Article
Genes identified in Asian SLE GWASs are also associated with SLE in Caucasian populations.
European journal of human genetics : EJHG - 1 Sept 2013
Wang Chuan, Ahlford Annika, Järvinen Tiina M, Nordmark Gunnel, Eloranta Maija-Leena, Gunnarsson Iva, Svenungsson Elisabet, Padyukov Leonid, Sturfelt Gunnar, Jönsen Andreas, Bengtsson Anders A, Truedsson Lennart, Eriksson Catharina, Rantapää-Dahlqvist Solbritt, Sjöwall Christopher, Julkunen Heikki, Criswell Lindsey A, Graham Robert R, Behrens Timothy W, Kere Juha, Rönnblom Lars, Syvänen Ann-Christine, Sandling Johanna K
Abstract excerpt
Recent genome-wide association studies (GWASs) conducted in Asian populations have identified novel risk loci for systemic lupus erythematosus (SLE). Here, we genotyped 10 single-nucleotide polymorphisms (SNPs) in eight such loci and investigated their disease associations in three independent Caucasian SLE case-control cohorts recruited from Sweden, Finland and the United States. The disease associations of the...
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