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Article

Viral evolution sustains a dengue outbreak of enhanced severity.

Emerging microbes & infections - 1 Dec 2021

Inizan Catherine, Minier Marine, Prot Matthieu, O'Connor Olivia, Forfait Carole, Laumond Sylvie, Marois Ingrid, Biron Antoine, Gourinat Ann-Claire, Goujart Marie-Amélie, Descloux Elodie, Sakuntabhai Anavaj, Tarantola Arnaud, Simon-Lorière Etienne, Dupont-Rouzeyrol Myrielle

Abstract excerpt

Compared to the previous 2013-2014 outbreak, dengue 2016-2017 outbreak in New Caledonia was characterized by an increased number of severe forms associated with hepatic presentations. In this study, we assessed the virological factors associated with this enhanced severity. Whole-genome sequences were retrieved from dengue virus (DENV)-1 strains collected in 2013-2014 and from severe and non-severe patients in...

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Identifiers

PMID: 33686914
DOI: 10.1080/22221751.2021.1899057
PMCID: PMC8011692

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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