Article

Yellow fever vaccine propagation in primary human hepatocytes triggers antiviral and cytolytic responses

2026-01-21

Abstract excerpt

Yellow fever virus (YFV) infection can cause severe-to-fatal liver damage in humans, while immunization with the attenuated 17D vaccine strain has an excellent safety record, priming protective host immunity in the absence of pathology. To investigate virus-host correlates associated with these differential clinical outcomes, we combined YFV genome-level evolutionary analyses with investigations of vaccine and vir...

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Literature Corpus work: 1a0b920f-bb5c-5ff3-9ede-effadb78db04
DOI: 10.64898/2026.01.21.700765

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