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Isolation and molecular characterization of dengue virus clinical isolates from pediatric patients in New Delhi

7 Dec 2018

Abstract excerpt

OBJECTIVE: To characterize the in vitro replication fitness, viral diversity, and phylogeny of dengue viruses (DENV) isolated from Indian patients. METHODS: DENV was isolated from whole blood collected from patients by passaging in cell culture. Passage 3 viruses were used for growth kinetics in C6/36 mosquito cells. Parallel efforts also focused on the isolation of DENV RNA from plasma samples of the same...

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PMID: 30528666
DOI: 10.1016/j.ijid.2018.12.003

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