Article
Genome-wide association analysis identifies 30 new susceptibility loci for schizophrenia.
Nature genetics - 1 Nov 2017
Li Zhiqiang, Chen Jianhua, Yu Hao, He Lin, Xu Yifeng, Zhang Dai, Yi Qizhong, Li Changgui, Li Xingwang, Shen Jiawei, Song Zhijian, Ji Weidong, Wang Meng, Zhou Juan, Chen Boyu, Liu Yahui, Wang Jiqiang, Wang Peng, Yang Ping, Wang Qingzhong, Feng Guoyin, Liu Benxiu, Sun Wensheng, Li Baojie, He Guang, Li Weidong, Wan Chunling, Xu Qi, Li Wenjin, Wen Zujia, Liu Ke, Huang Fang, Ji Jue, Ripke Stephan, Yue Weihua, Sullivan Patrick F, O'Donovan Michael C, Shi Yongyong
Abstract excerpt
We conducted a genome-wide association study (GWAS) with replication in 36,180 Chinese individuals and performed further transancestry meta-analyses with data from the Psychiatry Genomics Consortium (PGC2). Approximately 95% of the genome-wide significant (GWS) index alleles (or their proxies) from the PGC2 study were overrepresented in Chinese schizophrenia cases, including ∼50% that achieved nominal...
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