Article
Rare Recurrent Variants in Noncoding Regions Impact Attention-Deficit Hyperactivity Disorder (ADHD) Gene Networks in Children of both African American and European American Ancestry.
Genes - 22 Feb 2021
Liu Yichuan, Chang Xiao, Qu Hui-Qi, Tian Lifeng, Glessner Joseph, Qu Jingchun, Li Dong, Qiu Haijun, Sleiman Patrick, Hakonarson Hakon
Abstract excerpt
Attention-deficit hyperactivity disorder (ADHD) is a neurodevelopmental disorder with poorly understood molecular mechanisms that results in significant impairment in children. In this study, we sought to assess the role of rare recurrent variants in non-European populations and outside of coding regions. We generated whole genome sequence (WGS) data on 875 individuals, including 205 ADHD cases and 670 non-ADHD...
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