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Mutation burden analysis of six common mental disorders in African Americans by whole genome sequencing.

Human molecular genetics - 10 Nov 2022

Liu Yichuan, Qu Hui-Qi, Chang Xiao, Qu Jingchun, Mentch Frank D, Nguyen Kenny, Tian Lifeng, Glessner Joseph, Sleiman Patrick M A, Hakonarson Hakon

Abstract excerpt

Mental disorders present a global health concern and have limited treatment options. In today's medical practice, medications such as antidepressants are prescribed not only for depression but also for conditions such as anxiety and attention deficit hyperactivity disorder (ADHD). Therefore, identifying gene targets for specific disorders is important and offers improved precision. In this study, we performed a...

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Identifiers

PMID: 35642741
DOI: 10.1093/hmg/ddac129

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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