Aspergillosis due to voriconazole highly resistant Aspergillus fumigatus and recovery of genetically related resistant isolates from domiciles.

doi:10.1093/cid/cit320

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Aspergillosis due to voriconazole highly resistant Aspergillus fumigatus and recovery of genetically related resistant isolates from domiciles.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America - 1 Aug 2013

van der Linden Jan W M, Camps Simone M T, Kampinga Greetje A, Arends Jan P A, Debets-Ossenkopp Yvette J, Haas Pieter J A, Rijnders Bart J A, Kuijper Ed J, van Tiel Frank H, Varga János, Karawajczyk Anna, Zoll J, Melchers Willem J G, Verweij Paul E

Abstract excerpt

BACKGROUND: Azole resistance is an emerging problem in Aspergillus fumigatus and complicates the management of patients with Aspergillus-related diseases. Selection of azole resistance may occur through exposure to azole fungicides in the environment. In the Netherlands a surveillance network was used to investigate the epidemiology of resistance selection in A. fumigatus. METHODS: Clinical A. fumigatus isolates...

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PMID: 23667263
DOI: 10.1093/cid/cit320

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