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Article

A Workflow for Selection of Single Nucleotide Polymorphic Markers for Studying of Genetics of Ischemic Stroke Outcomes.

Genes - 25 Feb 2021

Khvorykh Gennady, Khrunin Andrey, Filippenkov Ivan, Stavchansky Vasily, Dergunova Lyudmila, Limborska Svetlana

Abstract excerpt

In this paper we propose a workflow for studying the genetic architecture of ischemic stroke outcomes. It develops further the candidate gene approach. The workflow is based on the animal model of brain ischemia, comparative genomics, human genomic variations, and algorithms of selection of tagging single nucleotide polymorphisms (tagSNPs) in genes which expression was changed after ischemic stroke. The workflow...

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Identifiers

PMID: 33668793
DOI: 10.3390/genes12030328
PMCID: PMC7996278

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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