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Examination of Genetic Variants Revealed from a Rat Model of Brain Ischemia in Patients with Ischemic Stroke: A Pilot Study.

Genes - 30 Nov 2021

Khrunin Andrey V, Khvorykh Gennady V, Rozhkova Alexandra V, Koltsova Evgeniya A, Petrova Elizaveta A, Kimelfeld Ekaterina I, Limborska Svetlana A

Abstract excerpt

Although there has been great progress in understanding the genetic bases of ischemic stroke (IS), many of its aspects remain underexplored. These include the genetics of outcomes, as well as problems with the identification of real causative loci and their functional annotations. Therefore, analysis of the results obtained from animal models of brain ischemia could be helpful. We have developed a bioinformatic...

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PMID: 34946887
DOI: 10.3390/genes12121938
PMCID: PMC8701352

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