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Clinical implications of copy number alteration detection using panel-based next-generation sequencing data in myelodysplastic syndrome.

Leukemia research - 1 Apr 2021

Kim Yoo-Jin, Jung Seung-Hyun, Hur Eun-Hye, Choi Eun-Ji, Lee Kyoo-Hyung, Park Hyeon-Chun, Kim Hye Joung, Kwon Yong-Rim, Park Silvia, Lee Sug Hyung, Chung Yeun-Jun, Lee Je-Hwan

Abstract excerpt

Recent advancements in next-generation sequencing (NGS) technologies allow the simultaneous identification of targeted copy number alterations (CNAs) as well as somatic mutations using the same panel-based NGS data. We investigated whether CNAs detected by the targeted NGS data provided additional clinical implications, over somatic mutations, in myelodysplastic syndrome (MDS). Targeted deep sequencing of 28...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33667811
DOI: 10.1016/j.leukres.2021.106540

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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