Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Single-cell DNA sequencing reveals complex mechanisms of resistance to quizartinib

5 Mar 2021

Abstract excerpt

Key Points Single-cell sequencing exposes previously unmeasurable complexity of tumor heterogeneity and clonal evolution on quizartinib. Single-cell sequencing reveals on- and off-target mechanisms of resistance to quizartinib, which can preexist therapy.

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Genomics and Diagnostics
Share to Lung Cancer Treatments and Mutations
Share to Pancreatic and Hepatic Oncology Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 33666651
DOI: 10.1182/bloodadvances.2020003398

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Single-cell DNA sequencing reveals complex mechanisms of resistance to quizartinibPMID 33666651Read ↗

Drug resistance: origins, evolution and characterization of genomic clones and the tumor ecosystem to optimize precise individualized therapySemantic proximity Read ↗

The landscape of actionable genomic alterations in cell-free circulating tumor DNA from 21,807 advanced cancer patientsSemantic proximity Read ↗

Single-cell RNA sequencing and bioinformatics as tools to decipher cancer heterogenicity and mechanisms of drug resistanceSemantic proximity Read ↗

Heterogeneous resistance to quizartinib in acute myeloid leukemia revealed by single-cell analysisSemantic proximity Read ↗

Delineating cancer evolution with single-cell sequencing.Semantic proximity Read ↗

Single whole genome sequencing analysis blazes the trail for precision medicine.Semantic proximity Read ↗

Single-cell mutational profiling and clonal phylogeny in cancer.Semantic proximity Read ↗

Single-cell DNA-seq depicts clonal evolution of multiple driver alterations in osimertinib-resistant patients.Semantic proximity Read ↗

The Landscape of Actionable Genomic Alterations in Cell-Free Circulating Tumor DNA from 21,807 Advanced Cancer Patients.Semantic proximity Read ↗

Tumor Heterogeneity, Single-Cell Sequencing, and Drug ResistanceSemantic proximity Read ↗

Genome-wide segregation of single nucleotide and structural variants into single cancer cells.Semantic proximity Read ↗

Tumor Evolution as a Therapeutic TargetSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.