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Article

Heterogeneous resistance to quizartinib in acute myeloid leukemia revealed by single-cell analysis

11 May 2017

Abstract excerpt

internal tandem duplication mutations at the time of acquired resistance to the FLT3 inhibitor quizartinib. These findings establish that clinical resistance to quizartinib is highly complex and reflects the underlying clonal heterogeneity of AML.

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Identifiers

PMID: 28490572
DOI: 10.1182/blood-2016-04-711820

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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