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The landscape of actionable genomic alterations in cell-free circulating tumor DNA from 21,807 advanced cancer patients

2017-12-12

Abstract excerpt

Cell-free DNA (cfDNA) sequencing provides a non-invasive method for obtaining actionable genomic information to guide personalized cancer treatment, but the presence of multiple alterations in circulation related to treatment and tumor heterogeneity pose analytical challenges. We present the somatic mutation landscape of 70 cancer genes from cfDNA deep-sequencing analysis of 21,807 patients with treated, late-stag...

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Literature Corpus work
dae53a5c-0f30-5b47-981c-06425d21c692
DOI
10.1101/233205
Open publication

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The landscape of actionable genomic alterations in cell-free circulating tumor DNA from 21,807 advanced cancer patientsDOI 10.1101/233205
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