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Article

RNA helicase DDX5 acts as a critical regulator for survival of neonatal mouse gonocytes.

Cell proliferation - 1 May 2021

Xia Qing, Cui Guizhong, Fan Ye, Wang Xiuqin, Hu Gongcheng, Wang Lisha, Luo Xi, Yang Lele, Cai Qingqing, Xu Kaibiao, Guo Wenjing, Gao Minghui, Li Yingying, Wu Ji, Li Wei, Chen Jiayu, Qi Huayu, Peng Guangdun, Yao Hongjie

Abstract excerpt

OBJECTIVES: Mammalian spermatogenesis is a biological process of male gamete formation. Gonocytes are the only precursors of spermatogonial stem cells (SSCs) which develop into mature spermatozoa. DDX5 is one of DEAD-box RNA helicases and expresses in male germ cells, suggesting that Ddx5 plays important functions during spermatogenesis. Here, we explore the functions of Ddx5 in regulating the specification of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33666296
DOI: 10.1111/cpr.13000
PMCID: PMC8088469

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