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Article

Isolation methodology is essential to the evaluation of the extracellular vesicle component of the senescence-associated secretory phenotype.

Journal of extracellular vesicles - 1 Feb 2021

Wallis Ryan, Josipovic Natasa, Mizen Hannah, Robles-Tenorio Arturo, Tyler Eleanor J, Papantonis Argyris, Bishop Cleo L

Abstract excerpt

A hallmark of senescence is the acquisition of an enhanced secretome comprising inflammatory mediators and tissue remodelling agents - the senescence-associated secretory phenotype (SASP). Through the SASP, senescent cells are hypothesised to contribute to both ageing and pathologies associated with age. Whilst soluble factors have been the most widely investigated components of the SASP, there is growing...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33659050
DOI: 10.1002/jev2.12041
PMCID: PMC7892802

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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