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Article

Smoking and heart failure: a Mendelian randomization and mediation analysis.

ESC heart failure - 1 Jun 2021

Lu Yunlong, Xu Zhouming, Georgakis Marios K, Wang Zhen, Lin Hefeng, Zheng Liangrong

Abstract excerpt

AIMS: We performed a Mendelian randomization (MR) study to elucidate the associations of ever smoking, lifelong smoking duration, and smoking cessation with heart failure (HF) risk. METHODS AND RESULTS: We extracted genetic variants associated with smoking initiation, age at initiation of regular smoking, cigarettes per day, and smoking cessation from the genome-wide association study and Sequencing Consortium of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 33656795
DOI: 10.1002/ehf2.13248
PMCID: PMC8120408

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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