Article
Novel genetic variants in KIF16B and NEDD4L in the endosome-related genes are associated with nonsmall cell lung cancer survival.
International journal of cancer - 15 Jul 2020
Yang Sen, Tang Dongfang, Zhao Yu C, Liu Hongliang, Luo Sheng, Stinchcombe Thomas E, Glass Carolyn, Su Li, Shen Sipeng, Christiani David C, Wang Qiming, Wei Qingyi
Abstract excerpt
The endosome is a membrane-bound organ inside most eukaryotic cells, playing an important role in adaptive immunity by delivering endocytosed antigens to both MHC class I and II pathways. Here, by analyzing genotyping data from two published genome-wide association studies (GWASs), we evaluated associations between genetic variants in the endosome-related gene-set and survival of patients with nonsmall cell lung...
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