Article
Thai patients who fulfilled NCCN criteria for breast/ovarian cancer genetic assessment demonstrated high prevalence of germline mutations in cancer susceptibility genes: implication to Asian population testing.
Breast cancer research and treatment - 1 Jul 2021
Lertwilaiwittaya Pongtawat, Roothumnong Ekkapong, Nakthong Panee, Dungort Peerawat, Meesamarnpong Chutima, Tansa-Nga Warisara, Pongsuktavorn Khontawan, Wiboonthanasarn Supakit, Tititumjariya Warunya, Thongnoppakhun Wanna, Chanprasert Sirisak, Limwongse Chanin, Pithukpakorn Manop
Abstract excerpt
BACKGROUND: Germline genetic mutation plays a significant role in breast cancer susceptibility. The strength of such predisposition varies among ethnic groups across the globe, and clinical data from Asian population to develop a strategic approach to who should undergo a genetic test are lacking. METHODS: We performed a multigene test with next generation sequencing in Thai patients whose clinical history...
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