Article
The potential role of follicular helper T cells and helper T cells type 1 in Warthin tumour.
Pathology, research and practice - 1 Apr 2021
Kobayashi Yoshiaki, Kurose Nozomu, Guo Xin, Shioya Akihiro, Kitamura Morimasa, Tsuji Hiroyuki, Yamada Sohsuke
Abstract excerpt
Warthin tumour (WT) is a benign tumour of the salivary gland that proliferates in both glandular epithelial and lymphoid tissue components, and rarely exhibits cystic changes. T follicular helper cells (Tfh) are involved in the formation and maintenance of germinal centres, the differentiation of B cells into plasma cells, and the maintenance of helper T cell type 2 (Th2)-dominant humoral immune responses. T-bet...
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