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Factors impacting the benefits and pathogenicity of Th17 cells in the tumor microenvironment

23 Aug 2023

Abstract excerpt

Tumor development is closely associated with a complex tumor microenvironment, which is composed of tumor cells, blood vessels, tumor stromal cells, infiltrating immune cells, and associated effector molecules. T helper type 17 (Th17) cells, which are a subset of CD4+ T cells and are renowned for their ability to combat bacterial and fungal infections and mediate inflammatory responses, exhibit context-dependent...

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PMID: 37680632
DOI: 10.3389/fimmu.2023.1224269

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