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Article

Predictive Accuracy of a Polygenic Risk Score for Postoperative Atrial Fibrillation After Cardiac Surgery.

Circulation. Genomic and precision medicine - 1 Apr 2021

Kertai Miklos D, Mosley Jonathan D, He Jing, Ramakrishnan Abinaya, Abdelmalak Mark J, Hong Yurim, Shoemaker M Benjamin, Roden Dan M, Bastarache Lisa

Abstract excerpt

BACKGROUND: Postoperative atrial fibrillation (PoAF) remains a significant risk factor for increased morbidity and mortality after cardiac surgery. The ability to accurately identify patients at risk through clinical risk factors is limited. There is growing evidence that polygenic risk contributes significantly to PoAF and incorporating measures of genetic risk could enhance prediction. METHODS: A retrospective...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33647223
DOI: 10.1161/CIRCGEN.120.003269
PMCID: PMC8058298

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