Article
Use of a Polygenic Risk Score Improves Prediction of Myocardial Injury After Non-Cardiac Surgery.
Circulation. Genomic and precision medicine - 1 Aug 2020
Douville Nicholas J, Surakka Ida, Leis Aleda, Douville Christopher B, Hornsby Whitney E, Brummett Chad M, Kheterpal Sachin, Willer Cristen J, Engoren Milo, Mathis Michael R
Abstract excerpt
BACKGROUND: While postoperative myocardial injury remains a major driver of morbidity and mortality, the ability to accurately identify patients at risk remains limited despite decades of clinical research. The role of genetic information in predicting myocardial injury after noncardiac surgery (MINS) remains unknown and requires large scale electronic health record and genomic data sets. METHODS: In this...
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