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Article

Designing gene drives to limit spillover to non-target populations.

PLoS genetics - 1 Feb 2021

Greenbaum Gili, Feldman Marcus W, Rosenberg Noah A, Kim Jaehee

Abstract excerpt

The prospect of utilizing CRISPR-based gene-drive technology for controlling populations has generated much excitement. However, the potential for spillovers of gene-drive alleles from the target population to non-target populations has raised concerns. Here, using mathematical models, we investigate the possibility of limiting spillovers to non-target populations by designing differential-targeting gene drives,...

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Identifiers

PMID: 33630838
DOI: 10.1371/journal.pgen.1009278
PMCID: PMC7943199

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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