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Article

Controlling the frequency dynamics of homing gene drives for intermediate outcomes.

G3 (Bethesda, Md.) - 5 Feb 2025

Camm Benjamin J, Fournier-Level Alexandre

Abstract excerpt

Gene drives have enormous potential for solving biological issues by forcing the spread of desired alleles through populations. However, to safeguard from the potentially irreversible consequences on natural populations, gene drives with intermediate outcomes that neither fixate nor get removed from the population are of outstanding interest. To elucidate the conditions leading to intermediate gene drive...

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Identifiers

PMID: 39698831
DOI: 10.1093/g3journal/jkae300
PMCID: PMC11797013

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