Clonal expansion in non-cancer tissues.

Abstract excerpt

Cancer is a clonal disorder derived from a single ancestor cell and its progenies that are positively selected by acquisition of 'driver mutations'. However, the evolution of positively selected clones does not necessarily imply the presence of cancer. On the contrary, it has become clear that expansion of these clones in phenotypically normal or non-cancer tissues is commonly seen in association with ageing...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Anemia, Aplastic
• Share to Barrett Esophagus
• Share to Clonal Hematopoiesis