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Article

Prevalence of UGT1A1 (TA)n promoter polymorphism in Panamanians neonates with G6PD deficiency.

Journal of genetics - 1 Jan 2020

Chávez-Peña Teresa, Martínez-Camberos Alejandra, Cossio-Gurrola Gladys, Arámbula-Meraz Eliakym, Herrera-Rodríguez Indira, Romo-Martínez Enrique, García-Magallanes Noemi

Abstract excerpt

A relationship between the polymorphism in promoter region of the UGT1A1 gene and the development of jaundice has been demonstrated recently. This polymorphism leads to 30% of normal rate transcription initiation of UGT1A1 gene, thus decreasing the bilirubin glucuronidation. The combination of the G6PD deficiency and polymorphism in neonates and adults may causepronounced hyperbilirubinaemias. The aim of this...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 33622990

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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