Article
Association between the Specific UGT1A1 Promoter Sequence Variant (c-3279T>G) and Unconjugated Neonatal Hyperbilirubinemia.
Journal of tropical pediatrics - 1 Dec 2016
Tomerak Rania Hosny, Helal Nahed Fahmy, Shaker Olfat Gameel, Yousef Mohamed Abdelhamid
Abstract excerpt
We investigated the association between c-3279T>G and unconjugated neonatal hyperbilirubinemia. In all, 141 neonates were recruited; 63 had hyperbilirubinemia necessitating treatment, and 78 with bilirubin < 7 mg/dl served as the control group. The frequency of occurrence of c-3279T > G allele was significantly higher in the hyperbilirubinemic (49.2%) than in the control group (25.6%). The homozygous (p = 0.001,...
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