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Article

(TA)n UDP-glucuronosyltransferase 1A1 promoter polymorphism in Nigerian neonates.

Pediatric research - 1 Jan 2008

Kaplan Michael, Slusher Tina, Renbaum Paul, Essiet Dominic F, Pam Sunday, Levy-Lahad Ephrat, Hammerman Cathy

Abstract excerpt

Nigerian neonates have a high incidence of bilirubin encephalopathy. Glucose-6-phosphate dehydrogenase (G-6-PD) deficiency is prevalent in this population. (TA)7 promoter polymorphism in the gene encoding the bilirubin conjugating enzyme UDP-glucuronosyltransferase 1A1 (UGT1A1) potentiates hyperbilirubinemia in G-6-PD deficient neonates. We studied (TA)n allele frequency to determine, at least in part, its...

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Source

Identifiers

PMID: 18043502
DOI: 10.1203/PDR.0b013e31815b8e7e

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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