Article
Neonatal jaundice and bilirubin UDP-glucuronosyl transferase 1A1 gene polymorphism in Turkish patients.
Basic & clinical pharmacology & toxicology - 1 Apr 2006
Babaoglu Melih O, Yigit Sule, Aynacioglu A Sukru, Kerb Reinhold, Yurdakok Murat, Bozkurt Atila
Abstract excerpt
Bilirubin uridine diphosphate-glucuronosyltransferase (B-UGT) is the rate-limiting enzyme for the conjugation of bilirubin with glucuronic acid in its excretion process into the bile. Variations in B-UGT gene (UGT-1A1) have been related to disorders characterised by hyperbilirubinaemia. The aim o...
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