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Novel Carrier-Free Nanomedicine for Regulating Macrophage Phenotype to Amplify Anti-Tumor Photoimmunotherapy.

Small (Weinheim an der Bergstrasse, Germany) - 1 Sept 2025

Xiang Jingfeng, Suo Meng, Lan Jiangli, Ning Shipeng, Liu Huan, Hong Wei, Liang Jing, Zheng Jianqiu, Zhu Daoming, Mo Jianlan

Abstract excerpt

Photoimmunotherapy presents a significant development potential both in inducing anti-tumor immunity and regulating the tumor microenvironment. However, the immunosuppressive tumor microenvironment (ITM) severely impedes the infiltration and functional activity of immune cells, while conventional immunotherapy strategies often fall short of inducing a potent and sustained anti-tumor immune response. Here, stable...

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PMID: 40746212
DOI: 10.1002/smll.202505304

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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