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Article

Molecular Pathogenesis of Pancreatic Cancer.

Progress in molecular biology and translational science - 1 Jan 2016

Grant T J, Hua K, Singh A

Abstract excerpt

Pancreatic cancers arise predominantly from ductal epithelial cells of the exocrine pancreas and are of the ductal adenocarcinoma histological subtype (PDAC). PDAC is an aggressive disease associated with a poor clinical prognosis, weakly effective therapeutic options, and a lack of early detection methods. Furthermore, the genetic and phenotypic heterogeneity of PDAC complicates efforts to identify universally...

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Identifiers

PMID: 27865459
DOI: 10.1016/bs.pmbts.2016.09.008
PMCID: PMC6260831

Genes

KRAS
SMAD4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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