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Article

The genetics of alcohol dependence and alcohol-related liver disease.

Journal of hepatology - 1 Jan 2017

Stickel Felix, Moreno Christophe, Hampe Jochen, Morgan Marsha Y

Abstract excerpt

The susceptibility to developing alcohol dependence and significant alcohol-related liver injury is determined by a number of constitutional, environmental and genetic factors, although the nature and level of interplay between them remains unclear. The familiality and heritability of alcohol dependence is well-documented but, to date, no strong candidate genes conferring increased risk have emerged, although...

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Share to Alcohol Dehydrogenase
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Share to Gene-Environment Interaction

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to PNPLA3 gene

Share to Genetic Predisposition to Disease

Share to Liver Diseases, Alcoholic

Share to Polymorphism, Genetic

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Source

Identifiers

PMID: 27575312
DOI: 10.1016/j.jhep.2016.08.011

Genes

MBOAT7
PNPLA3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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