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Article

Metabolic and Genetic Risk Factors Are the Strongest Predictors of Severity of Alcohol-Related Liver Fibrosis.

Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association - 1 Aug 2022

Israelsen Mads, Juel Helene Bæk, Detlefsen Sönke, Madsen Bjørn Stæhr, Rasmussen Ditlev Nytoft, Larsen Trine R, Kjærgaard Maria, Fernandes Jensen Mary Jo, Stender Stefan, Hansen Torben, Krag Aleksander, Thiele Maja

Abstract excerpt

BACKGROUND & AIMS: Individual risk for developing alcohol-related liver disease (ALD) varies greatly. We hypothesized that metabolic risk factors and genetic polymorphisms predict severity of ALD. METHODS: Biopsy-controlled, cross-sectional study in patients with a history of excessive drinking. We measured the homeostatic model assessment of insulin resistance (HOMA-IR), plasma triglycerides, high- and...

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Identifiers

PMID: 33279778
DOI: 10.1016/j.cgh.2020.11.038

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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