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Article

Prostate adenocarcinoma and COVID-19: The possible impacts of TMPRSS2 expressions in susceptibility to SARS-CoV-2.

Journal of cellular and molecular medicine - 1 Apr 2021

Cheng Jingliang, Zhou Ju, Fu Shangyi, Fu Jiewen, Zhou Baixu, Chen Hanchun, Fu Junjiang, Wei Chunli

Abstract excerpt

TMPRSS2 (OMIM: 602060) is a cellular protease involved in many physiological and pathological processes, and it facilitates entry of viruses such as SARS-CoV-2 into host cells. It is important to predict the prostate's susceptibility to SARS-CoV-2 infection in cancer patients and the disease outcome by assessing TMPRSS2 expression in cancer tissues. In this study, we conducted the expression profiles of the...

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Identifiers

PMID: 33609069
DOI: 10.1111/jcmm.16385
PMCID: PMC8013364

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