Article
Expression and co-expression analyses of TMPRSS2, a key element in COVID-19.
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology - 1 Feb 2021
Piva Francesco, Sabanovic Berina, Cecati Monia, Giulietti Matteo
Abstract excerpt
The ACE2 receptor is, so far, the best-known host factor for SARS-CoV-2 entry, but another essential element, the TMPRSS2 protease, has recently been identified. Here, we have analysed TMPRSS2 expression data in the lung correlating them with age, sex, diabetes, smoking habits, exposure to pollutant and other stimuli, in order to highlight which factors might alter TMPRSS2 expression, and thus impact the...
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