Article
Multi-omics highlights ABO plasma protein as a causal risk factor for COVID-19.
Human genetics - 1 Jun 2021
Hernández Cordero Ana I, Li Xuan, Milne Stephen, Yang Chen Xi, Bossé Yohan, Joubert Philippe, Timens Wim, van den Berge Maarten, Nickle David, Hao Ke, Sin Don D
Abstract excerpt
SARS-CoV-2 is responsible for the coronavirus disease 2019 (COVID-19) and the current health crisis. Despite intensive research efforts, the genes and pathways that contribute to COVID-19 remain poorly understood. We, therefore, used an integrative genomics (IG) approach to identify candidate genes responsible for COVID-19 and its severity. We used Bayesian colocalization (COLOC) and summary-based Mendelian...
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