Article
Virus-derived peptide inhibitors of the herpes simplex virus type 1 nuclear egress complex.
Scientific reports - 18 Feb 2021
Draganova Elizabeth B, Heldwein Ekaterina E
Abstract excerpt
Herpesviruses infect a majority of the human population, establishing lifelong latent infections for which there is no cure. Periodic viral reactivation spreads infection to new hosts while causing various disease states particularly detrimental in the immunocompromised. Efficient viral replication, and ultimately the spread of infection, is dependent on the nuclear egress complex (NEC), a conserved viral...
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