Article
Size-selective microcavity array for rapid and efficient detection of circulating tumor cells.
Analytical chemistry - 1 Aug 2010
Hosokawa Masahito, Hayata Taishi, Fukuda Yorikane, Arakaki Atsushi, Yoshino Tomoko, Tanaka Tsuyoshi, Matsunaga Tadashi
Abstract excerpt
Circulating tumor cells (CTCs) are tumor cells circulating in the peripheral blood of patients with metastatic cancer. Detection of CTCs has clinical significance in cancer therapy because it would enable earlier diagnosis of metastasis. In this research, a microfluidic device equipped with a size-selective microcavity array for highly efficient and rapid detection of tumor cells from whole blood was developed....
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