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Article

HLA-DQ and HLA-DRB1 alleles associated with Henoch-Schönlein purpura nephritis in Finnish pediatric population: a genome-wide association study.

Pediatric nephrology (Berlin, Germany) - 1 Aug 2021

Koskela Mikael, Nihtilä Julia, Ylinen Elisa, Kolho Kaija-Leena, Nuutinen Matti, Ritari Jarmo, Jahnukainen Timo

Abstract excerpt

BACKGROUND: The pathophysiology of Henoch-Schönlein purpura (HSP) is still unclear, but several findings suggest that genetic factors may influence disease susceptibility. We aimed to perform a genome-wide association study (GWAS) in pediatric HSP patients with an emphasis on severe HSP nephritis. METHODS: The study included 46 HSP patients, 42 of whom had undergone kidney biopsy. Forty-nine pediatric patients...

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Identifiers

PMID: 33591409
DOI: 10.1007/s00467-021-04955-7
PMCID: PMC8260528

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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