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Article

CD81 marks immature and dedifferentiated pancreatic β-cells

11 Feb 2021

Abstract excerpt

Islets of Langerhans contain heterogeneous populations of insulin-producing β-cells. Surface markers and respective antibodies for isolation, tracking, and analysis are urgently needed to study β-cell heterogeneity and explore the mechanisms to harness the regenerative potential of immature β-cells. We performed single-cell mRNA profiling of early postnatal mouse islets and re-analyzed several single-cell mRNA...

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Share to Diabetes and associated disorders
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 33582383
DOI: 10.1016/j.molmet.2021.101188

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