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Article

Evaluation of Surveyor nuclease for rapid identification of FKS genes mutations in Candida glabrata.

Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy - 1 Jun 2021

Khalifa Hazim O, Arai Teppei, Majima Hidetaka, Watanabe Akira, Kamei Katsuhiko

Abstract excerpt

INTRODUCTION: Infections with Candida glabrata have recently gained worldwide attention owing to its association with long hospitalizations and high mortality rates. This problem is highlighted when the infection is associated with echinocandin resistance, which is used for first-line therapy. Echinocandin resistance is exclusively attributed to functional mutations in FKS genes, and especially in hot spot (HS)...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33582033
DOI: 10.1016/j.jiac.2021.01.016

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