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Article

Rapid Detection of FKS-Associated Echinocandin Resistance in Candida glabrata.

Antimicrobial agents and chemotherapy - 1 Nov 2016

Zhao Yanan, Nagasaki Yoji, Kordalewska Milena, Press Ellen G, Shields Ryan K, Nguyen M Hong, Clancy Cornelius J, Perlin David S

Abstract excerpt

A novel and highly accurate diagnostic assay platform was established for rapid identification of FKS mutations associated with echinocandin resistance in Candida glabrata The assay platform uses allele-specific molecular beacon and DNA melt analysis following asymmetric PCR. A dual assay for FKS1 and FKS2 was developed to identify within 3 h the most common and clinically relevant resistance-associated...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27550360
DOI: 10.1128/AAC.01574-16
PMCID: PMC5075061

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Rapid Detection of FKS-Associated Echinocandin Resistance in Candida glabrata.PMID 27550360Read ↗

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