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Article

Characterising cancer-associated fibroblast heterogeneity in non-small cell lung cancer: a systematic review and meta-analysis.

Scientific reports - 12 Feb 2021

Irvine Andrew F, Waise Sara, Green Edward W, Stuart Beth, Thomas Gareth J

Abstract excerpt

Cancer-associated fibroblasts (CAFs) are a key component of the tumour microenvironment with evidence suggesting they represent a heterogeneous population. This study summarises the prognostic role of all proteins characterised in CAFs with immunohistochemistry in non-small cell lung cancer thus far. The functions of these proteins in cellular processes crucial to CAFs are also analysed. Five databases were...

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Identifiers

PMID: 33580106
DOI: 10.1038/s41598-021-81796-2
PMCID: PMC7881148

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