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Article

The role of cGAS/STING in intestinal immunity

12 Feb 2021

Abstract excerpt

The gastrointestinal tract is a highly complex microenvironment under constant interaction with potentially harmful pathogens. Inflammatory bowel disease (IBD) is an archetypical inflammatory disease, in which the intestinal epithelium, defective autophagy, endoplasmic reticulum stress and dysbiosis play a key role. Although no risk-mediating gene variants of STING (TMEM173) have been identified so far, several...

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PMID: 33577080
DOI: 10.1002/eji.202048777

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