Article
Tumor Mutational Patterns and Infiltrating Lymphocyte Density in Young and Elderly Patients With Breast Cancer.
Cancer genomics & proteomics - 1 Jan 2000
Nikolaidi Adamantia, Kotoula Vassiliki, Koliou Georgia-Angeliki, Giannoulatou Eleni, Papadopoulou Kyriaki, Zagouri Flora, Pentheroudakis George, Gogas Helen, Bobos Mattheos, Chatzopoulos Kyriakos, Oikonomopoulos Georgios, Pectasides Dimitrios, Saloustros Emmanouil, Arnogiannaki Niki, Nicolaou Irene, Papakostas Pavlos, Bompolaki Iliada, Aravantinos Gerasimos, Athanasiadis Ilias, Fountzilas George
Abstract excerpt
BACKGROUND/AIM: Age may pertain to different tumor genotype characteristics which may interfere with treatment efficacy and prognosis. We investigated the distribution and prognostic effect of mutations and tumor infiltrating lymphocyte (stromal TIL density) in young (≤35 years) and elderly (>65 years) early breast cancer patients. MATERIALS AND METHODS: Paraffin tumor genotypes of all clinical subtypes from 345...
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