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Multi-omics profiling of younger Asian breast cancers reveals distinctive molecular signatures

24 Apr 2018

Abstract excerpt

Breast cancer (BC) in the Asia Pacific regions is enriched in younger patients and rapidly rising in incidence yet its molecular bases remain poorly characterized. Here we analyze the whole exomes and transcriptomes of 187 primary tumors from a Korean BC cohort (SMC) enriched in pre-menopausal patients and perform systematic comparison with a primarily Caucasian and post-menopausal BC cohort (TCGA). SMC harbors...

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PMID: 29713003
DOI: 10.1038/s41467-018-04129-4

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