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Article

Replication of HLA class II locus association with susceptibility to podoconiosis in three Ethiopian ethnic groups.

Scientific reports - 8 Feb 2021

Gebresilase Tewodros, Finan Chris, Suveges Daniel, Tessema Tesfaye Sisay, Aseffa Abraham, Davey Gail, Hatzikotoulas Konstantinos, Zeggini Eleftheria, Newport Melanie J, Tekola-Ayele Fasil

Abstract excerpt

Podoconiosis, a debilitating lymphoedema of the leg, results from barefoot exposure to volcanic clay soil in genetically susceptible individuals. A previous genome-wide association study (GWAS) conducted in the Wolaita ethnic group from Ethiopia showed association between single nucleotide polymorphisms (SNPs) in the HLA class II region and podoconiosis. We aimed to conduct a second GWAS in a new sample...

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Identifiers

PMID: 33558538
DOI: 10.1038/s41598-021-81836-x
PMCID: PMC7870958

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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