Article
HLA class II locus and susceptibility to podoconiosis.
The New England journal of medicine - 29 Mar 2012
Tekola Ayele Fasil, Adeyemo Adebowale, Finan Chris, Hailu Elena, Sinnott Paul, Burlinson Natalia Diaz, Aseffa Abraham, Rotimi Charles N, Newport Melanie J, Davey Gail
Abstract excerpt
BACKGROUND: Podoconiosis is a tropical lymphedema resulting from long-term barefoot exposure to red-clay soil derived from volcanic rock. The World Health Organization recently designated it as a neglected tropical disease. Podoconiosis develops in only a subgroup of exposed people, and studies have shown familial clustering with high heritability (63%). METHODS: We conducted a genomewide association study of 194...
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