Article
Fine mapping of a major histocompatibility complex in ankylosing spondylitis: association of the HLA-DPA1 and HLA-DPB1 regions.
Arthritis and rheumatism - 1 Nov 2011
Díaz-Peña Roberto, Aransay Ana M, Bruges-Armas Jacome, López-Vázquez Antonio, Rodríguez-Ezpeleta Naiara, Mendibil Iñaki, Sánchez Alejandra, Torre-Alonso Juan Carlos, Bettencourt Bruno F, Mulero Juan, Collantes Eduardo, López-Larrea Carlos
Abstract excerpt
OBJECTIVE: To investigate the potential association of major histocompatibility complex (MHC) markers other than HLA-B27 with ankylosing spondylitis (AS). METHODS: A total of 603 patients with AS and 542 healthy control subjects, all of whom were HLA-B27 positive, were selected for this study based on clinical criteria. First, high-density genotyping across the MHC region (2,360 single-nucleotide polymorphisms...
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